Hyperkeratosis is a thickening outer layer of the skin. This outermost layer contains tough and protective protein called keratin and also usually accompanied in an increase granular layer. Basically, this skin thickening is often part of the skin's normal protection against rubbing, pressure and other forms of local irritation. The thickened skin is usually darker than the normal skin. Bacteria can grow in thick skin, often causing a distinct odor. It causes corns and bumps on hands and feet. The other hyperkeratosis can occur as part of the skin's defense against chronic (long-lasting) inflammation, radiation of sunlight and irritating chemicals. Less often, hyperkeratosis develops on skin that hasn't been irritated. These type of hyperkeratosis may be part of an inherited condition and that may begin soon after birth and can skin on large areas of the body.
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