Wednesday, 23 December 2015

Keratosis Follicularis (Darrier's disease)

keratosis Follicularis  also known as Darrier's disease (DD) or Darrier -White disease is an autosomal dominant disorder. Most of patients have family history of the disease. It is characterized by dark crusty patches on the skin, sometimes contains pus. The crusty patches also called keratosis papules. The first skin lesions typically occur in teenage years and frequently associated with pruritus. The skin lesions are characterized bu persistent, greasy, scaly papules (small pumps) which tend to occur over the "seborrhoeic" areas of the face ( scalp margins, forehead, ears, around the nostrils and sides of nose, eyebrows, and beard area), neck and central chest and back. If several of small papules grow together they may form larger warty lesions which can become quite smelly within skin folds. the scalps is often affected with a heavily crusted rash which can be similar to seborrhoeic dermatitis but is usually harsher to touch.



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